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A short, swift update

Today was a day from hell at work. I'll post more another time if I get the chance.

What started it downhill was, of course, mostly unrelated to work. One of my first emails of the day came from our formulary manager, who forwarded a message from the FDA: "FDA asks Pfizer to remove Bextra (valdecoxib) from the market."

I was worried about this. Bextra is what keeps me functional. I've had a form of arthritis for 15 years now, and Bextra is (I think) the seventh medication I've been on. Things work for a bit, then they don't work so well. Bextra's still working. I have about 2 and a half months left, and then I'll have to try something else. Problem is, everything else is likely to be inferior.

Comments

( 12 comments — Leave a comment )
glenbarnett
Apr. 8th, 2005 02:17 am (UTC)

Do you know what the problem with it is?

Maybe there's something similar that can be had.
sethcohen
Apr. 8th, 2005 04:17 pm (UTC)
cardiac issues
It seems to be a class effect. It's not yet off the market outside the US. Maybe I can import it.
cellio
Apr. 8th, 2005 02:56 am (UTC)
Argh.

I assume that when the FDA says to remove something from the market, they mean Right Now?
glenbarnett
Apr. 8th, 2005 03:23 am (UTC)

Generally that's so.

If that didn't imply some potentially serious issue, I'd have suggested a dispensing robot malfunction ("No, I have no idea what the robot did with the six month supply of that drug. Do you think someone could have disposed of it already?") as a quick solution.


sethcohen
Apr. 8th, 2005 04:17 pm (UTC)
I agree with that in theory, but disagree ethically. Besides, we didn't have that much of it sitting around.
glenbarnett
Apr. 11th, 2005 05:38 am (UTC)

Yeah. 'twas only in imaginary fun.


leahmiriam
Apr. 8th, 2005 03:30 am (UTC)
I hear you. I refuse to get rid of the Vioxx I paid $150 for when my insurance plan refused to cover it pre-removal from the market. Hard to believe it could cost that much but I gladly paid knowing it is the only drug that allows me to stand upright when tricky discs go haywire.

When than happens I will use some from my stash. The Advil does nothing.

Pretty soon what will be left to take care of all of our aches and pains?
sethcohen
Apr. 8th, 2005 04:18 pm (UTC)
Pretty soon what will be left to take care of all of our aches and pains?
Morphine, and lots of it.
leahmiriam
Apr. 8th, 2005 04:22 pm (UTC)
Re: Pretty soon what will be left to take care of all of our aches and pains?
Yeah but it's hard to do much of anything else while on it. At least for me.
sethcohen
Apr. 8th, 2005 04:37 pm (UTC)
Re: Pretty soon what will be left to take care of all of our aches and pains?
Okay, so I forgot "...and amphetamines."
morganminstrel
Apr. 8th, 2005 06:17 am (UTC)
Well, I heard on the radio on the way home from work that it's official--Bextra has been pulled from the market. So, what are you going to do? It sounds like Celebrex is all that's left--can you use that?

Hope someone at Pfizer or somewhere gets off their duffs and make a new pain reliever that doesn't contribute to heart problems...
bodnej
Apr. 8th, 2005 02:14 pm (UTC)
Don't hold your breath waiting for new painkilling drugs; all of the Cox-2 inhibitors are likely to cause heart problems:

http://www.corante.com/pipeline/archives/2004/10/07/how_bad_are_the_cox2_inhibitors_anyway.php
(search his site for Vioxx for more info. Derek Lowe has a PhD in organic chemistry and works on new drug development)
( 12 comments — Leave a comment )