What started it downhill was, of course, mostly unrelated to work. One of my first emails of the day came from our formulary manager, who forwarded a message from the FDA: "FDA asks Pfizer to remove Bextra (valdecoxib) from the market."
I was worried about this. Bextra is what keeps me functional. I've had a form of arthritis for 15 years now, and Bextra is (I think) the seventh medication I've been on. Things work for a bit, then they don't work so well. Bextra's still working. I have about 2 and a half months left, and then I'll have to try something else. Problem is, everything else is likely to be inferior.